“Lupoid hepatitis” in SLE patients and mice with experimental lupus
نویسندگان
چکیده
منابع مشابه
Hepatitis Lupoid or Lupus Hepatitis: A Challenging Diagnosis
Systemic lupus Erythematosus (SLE) is a chronic inflammatory disease that affects multiple organs and systems such as skin, joints, kidneys, cardiovascular and central nervous systems. Twenty five to fifty percent of the patients with the diagnosis of SLE develop abnormal liver test during the course of the disease, being the main causes: hepatotoxic drugs, viral hepatitis and fatty liver disea...
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Oral manifestations and its associated factors in Iranian Systemic lupus erythematosus (SLE) patients
Background and Objective: Due to the overall wide range of oral manifestations and the lack of comprehensive categorized information in Iran, this study was performed to investigate the prevalence of different oral manifestations and report their possible associated factors in patients with SLE. Materials and Methods: This cross-sectional study was performed on 96 SLE patients referred to two ...
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B cells are essential to the development of systemic lupus erythematosus (SLE). The chimeric monoclonal antibody rituximab depletes B cells by targeting the pan-B-cell surface marker CD20. Preliminary experience with this agent in SLE and other autoimmune diseases has been encouraging. Controlled trials in SLE will be necessary to determine whether rituximab is useful therapy in this disease, a...
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In a patient with systemic lupus erythematosus (SLE), we considered the diagnosis of autoimmune hepatitis (AIH) in view of raised serum aminotransferases, hypergammaglobulinaemia, antinuclear antibodies (titre 1:10,240), seronegativity of markers for viral hepatitis and absence of recent hepatotoxic drug usage. The diagnosis of AIH was supported by using the scoring system, recently developed b...
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ژورنال
عنوان ژورنال: Clinical Immunology
سال: 2016
ISSN: 1521-6616
DOI: 10.1016/j.clim.2016.07.007